Fibroblasts are connective tissue cells responsible for synthesizing the extracellular matrix, which is essential in regulating intercellular communication. These cells synthesize collagen and elastin, essential proteins that provide tissues with structural support and elasticity, respectively.
The terms “fibroblast” and “fibrocyte” refer to the same type of cell, the former (suffix -blast) referring to the metabolically activated state. Fibroblasts function in wound healing by reconstructing the extracellular matrices in new tissue formation.
Fluorescent-dyed deer skin fibroblast cells